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Gamma probe-guided surgery protocol for Tc-99m MAA |
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| Tc-99m MAA Lesion Localization with image/endoscopy guidance |
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| Radiopharmaceutical Dose/Administration |
• Tc-99m MAA • 0.1 mCi (.0037 MBq)/direct injection |
| Standard Imaging Protocol |
• No nuclear medicine imaging needed |
| Timing of Surgical Exploration |
• Within 6 h post-injection |
| Patient Preparation |
• Not required |
| Gamma Probe |
• Standard medium-energy gamma probe |
| System set-up |
• Analyzer Settings: Photopeak: 140 keV, Window: 20%, Threshold: 136 keV (In commercial systems this is a default setting) • Verify calibration and settings of the system • Cover the probe with sterile plastic sleeve |
| Intra-operative Use |
• Probe survey at counts- per-second mode (Dynamic pitch range feed-back helpful) • Hot-spot confirmation with TBR>1.5 at 10-second count mode (TBR ratio feed-back helpful) Avoid simultaneous electrocautery use |
Gulec et al. World Journal of Surgical Oncology 2007 5:43 doi:10.1186/1477-7819-5-43 |
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